Issue: While trying to update the page layout for any page in SharePoint, I realized that Page Layouts button was disabled!
Reason: There can be many reasons for this, but here are the first things to check
1. SharePoint Server Publishing Infrastructure feature should be activated at site collection level.
2. SharePoint server publishing feature should be activated at site level.
You should now be able to see that button in top ribbon under Page Actions tab.
But, if you are like me and working in SharePoint 2010 and if you see the option after publishing feature is enabled, but if it is DISABLED, try this –
Click on ‘Save and Keep Editing’
BAM! It’s available now.